J Neurosurg. 2004 Dec;101(6):960-9.
Intraoperative infrared imaging of brain tumors.
Gorbach AM, Heiss JD, Kopylev L, Oldfield EH.
National Institute of Neurological Disorders and Stroke, Bioengineering and Physical Science, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-5766, USA.
Although clinical imaging defines the anatomical relationship between a brain tumor and the surrounding brain and neurological deficits indicate the neurophysiological consequences of the tumor, the effect of a brain tumor on vascular physiology is less clear. … Brain tumors induce changes in cerebral blood flow (CBF) in the cortex, which can be made visible by performing infrared imaging during cranial surgery. A reduction in CBF beyond the tumor margin improves after removal of the lesion.